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Index > Protein center > Phf1(Gene name) > Mouse
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  • Phf1 (Gene name),
  • PHD finger protein 1 (Protein name ),  PHF1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Phf1(Plc1;Tctex-3;Tctex3);
    Protein name:
    PHD finger protein 1(Protein PHF1);
    Alternative:
    T-complex testis-expressed 3;Polycomb-like protein 1(mPCl1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with the PRC2/EED-EZH2 complex (By similarity). Interacts with CHMP1.
    Function:
    Transcriptional repressor. May promote methylation of histone H3 on 'Lys-27' by the PRC2 complex.
    Subcellular Location:
    Nucleus Cytoplasm cytoskeleton centrosome Localizes specifically to the promoters of numerous target genes. Co-localizes with NEK6 in the centrosome.
    Protein Attributes:
    Sequence length:
    559
    Sequence:
    50:
    MAQLPRLSRL | GAPSLWDPAS | PAPTSGPRPR | LWEGQDVLAR | WTDGLLYLGT | 
    100:
    IKKVDSAREV | CLVQFEDDSQ | FLVLWKDISP | AALPGEELLC | CVCRSETVVP | 
    150:
    GNRLVSCEKC | RHAYHQDCHV | PRAPAPGEGE | GASWVCRQCV | FAIATKRGGA | 
    200:
    LKKGPYARAM | LGMKLSLPYG | LKGLDWDAGH | LSNRQQSYCY | CGGPGEWNLK | 
    250:
    MLQCRSCLQW | FHEACTQCLS | KPLLYGDRFY | EFECCVCRGG | PEKVRRLQLR | 
    300:
    WVDVAHLVLY | HLSVCCKKKY | FDFDREILPF | TSENWDSLLL | GELSDTPKGE | 
    350:
    RSSQLLSALN | SHKDRFISGR | EIKKRKCLFG | LHARTPPPVE | LLTGDGAPTS | 
    400:
    FPSGQGPGGG | VSRPLGKRWR | SEPEPLRRRQ | KGKVEELGPP | TAAHSRHGSR | 
    450:
    EQRALQASVS | PPPPSPNQSY | EGSSGYNFRP | TDARCLPSSP | IRMFASFHPS | 
    500:
    ASTAGTSGDS | EPPDRSPLGL | HIGFPTDTPK | SSPHSVTASS | SSVPALTPGF | 
    550:
    SRHSPPSPLC | RSLSPGTGGG | VRGGVSYLSR | GDPVRVLARR | VRPDGSVQYL | 
    559:
    VEWGGGGIF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    SMR:
    UniGene:
    UniGene:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Protein PHF1
    Cat.:
    E13279m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Protein PHF1
    Cat.:
    E13279h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Protein PHF1
    Cat.:
    U13279m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Protein PHF1
    Cat.:
    U13279h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Protein PHF1
    Polyclonal Antibody for Mouse Protein PHF1
    Monoclonal Antibody for Mouse Protein PHF1
    Monoclonal Antibody for Mouse Protein PHF1
    Protein for Mouse Protein PHF1
    Protein for Mouse Protein PHF1

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Tctex3, related to Drosophila polycomblike, is expressed in male germ cells and mapped to the mouse T-complex."
      Kawakami S. , Mitsunaga K. , Kikuti Y.Y. , Ando A. , Inoko H. , Yamamura K. , Abe K.
      Mamm. Genome9:874-880(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Testis.
    2. 2.
      "Misexpression of Polycomb-group proteins in Xenopus alters anterior neural development and represses neural target genes."
      Yoshitake Y. , Howard T.L. , Christian J.L. , Hollenberg S.M.
      Dev. Biol.215:375-387(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: NIH Swiss.
    3. 3.
      "CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression."
      Stauffer D.R. , Howard T.L. , Nyun T. , Hollenberg S.M.
      J. Cell Sci.114:2383-2393(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CHMP1
    4. 4.
      "Role of hPHF1 in H3K27 methylation and Hox gene silencing."
      Cao R. , Wang H. , He J. , Erdjument-Bromage H. , Tempst P. , Zhang Y.
      Mol. Cell. Biol.28:1862-1872(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: H3K36ME3-BINDING
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